Mechanism-based pharmacodynamic modeling of S(-)-atenolol

Therapeutic area :

Steeg T.J.v., Freijer J., Danhof M.  and Lange E. C. d., Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther., 324(3): 1234-1242., 2008. [Link to publication]