Publications & Presentations in the therapeutic area :

Treatment efficacy of Pioglitazone in Combination Therapy

Post T., Winter W.d., Jongh J.d., Urquhart R., Moules I., Eckland D. and Danhof M., Treatment efficacy of Pioglitazone in Combination Therapy on Disease Progression in Type 2 Diabetes Mellitus over a two-year period. ADA.(2005).

Cascading Disease Progression Analysis in Type 2 Diabetes

Winter W.d., Cascading Disease Progression Analysis in Type 2 Diabetes: Integrating multiple biomarkers into single mechanism-based model. PharmSciFair.(2005).

Treatment Efficacy of Combination-Therapy

Post T.M., Winter W.d., Jongh J.d., Moules I., Urquhart R., Eckland D. and Danhof M., Treatment Efficacy of Combination-Therapy based on a Mechanistic Characterisation of Disease Processes in Type 2 Diabetes Mellitus over a two-year period. Figon.(2005).

Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus and Pioglitazone Treatment Effects

Winter W.d., Post T., Jongh J.d., Urquhardt R., Moules I., Eckland D. and Danhof M.A., Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus and Pioglitazone Treatment Effects. PAGE.(2004). [Link to publication]

Disease Progression Analysis for Type 2 Diabetes Mellitus

Winter W.d., Post T.M., Jongh J.d., Moules I., Urquhart R., Eckland D. and Danhof M., Disease Progression Analysis for Type 2 Diabetes Mellitus: Bridging Therapeutic Intervention and Disease Outcome. Figon.(2004).

Towards a Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus

Winter W.d., Jongh J.d., Eckland D. and Danhof M., Towards a Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus. ASCPT.(2004).

Mechanistic Disease Progression Analysis Indicates that Pioglitazone Prevents the Progression of T2DM

Winter W.d., Jongh J.d., Moules I., Urquhart R., Eckland D. and Danhof M., Mechanistic Disease Progression Analysis Indicates that Pioglitazone Prevents the Progression of T2DM. ADA.(2004).

Mechanistic Disease Progression Analysis

Winter W.d., Jongh J.d., Urquhart R., Moules I., Eckland D. and Danhof M., Mechanistic Disease Progression Analysis Indicates that Pioglitazone Impedes the Progression of Type 2 Diabetes Mellitus (T2DM) in Combination Therapy with Sulphonylurea and Metformin. EASD.(2004).

Integrating multiple biomarker into a single mechanistic model cascade of disease processes

Winter W.d., Jongh J.d.,  and Danhof M., Integrating multiple biomarker into a single mechanistic model cascade of disease processes. cost b15.(2004).