A systems pharmacology model accounting for tracer dynamics throughout the APP pathway

Therapeutic area :

Maanen E.v., Steeg T.v., Stone J., Dobrowolska J., Michener M., Savage M., Kennedy M., Bateman R., Kleijn H. and Danhof M., A systems pharmacology model accounting for tracer dynamics throughout the APP pathway: Implications for interpretation of BACE inhibition response in CMP rhesus monkeys. Noordwijkerhout.(2014)