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Assessment of the use of complex baseline models in preclinical safety screening

Therapeutic area :

Steeg T. v., Strougo A., Ploeger B. and Graaf P. v. d., Assessment of the use of complex baseline models in preclinical safety screening: Application of the van der Pol oscillator model to describe heart rate effects in rats. PAGE.(2008). [Link to publication]

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Anesthesiology Paediatrics Cardiovascular Peripheral Nervous System Gastrointestinal Diseases Diabetes Anti-infectives and immunology Oncology Methods Endocrinology/Sexual health CNS Pain Safety pharmacology General modelling Lung Diseases Blood disorders Biologicals