Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation

Therapeutic area :

Goto, A., Tagawa, Y., Moriya, Y., Sato, S., Furukawa, Y., Wakabayashi, T., Tsukamoto T., Jongh J.d, Steeg T.J.v., Moriwaki T., Asahi, S. Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation. Biopharmaceutics & Drug Disposition, 373–380, 2017. [Link to publication]