Novel maturation function to capture the maturation of hepatic clearance in Preterm and Term Neonates to older infants, children and Adults: application to paracetamol and metabolites PK.

Therapeutic area :

Wu Y.,  Völler S., Goulooze S.C.,  Allegaert K., Sherwin C.M. T., Rongen van A., Roofthooft  D.W.E., Simons S.H.P., Tibboel D., Flint R.B., Anker van den J.N.,  Knibbe C.A.J. Novel maturation function to capture the maturation of hepatic clearance in Preterm and Term Neonates to older infants, children and Adults: application to paracetamol and metabolites PK. PAGE 2024 [Link to publication]