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A novel integrated QSP model of in vivo human glucose regulation to support the development of a glucagon/GLP-1 dual agonist.

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Bosch R., Petrone M., Arends R., Vicini P., Sijbrands E.J.G., Hoefman S., Snelder N. A novel integrated QSP model of in vivo human glucose regulation to support the development of a glucagon/GLP-1 dual agonist. CPT Pharmacometrics Syst Pharmacol, 2021. [Link to publication]

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Methods CNS Anti-infectives and immunology Oncology Gastrointestinal Diseases Safety pharmacology Cardiovascular Pain Peripheral Nervous System Paediatrics General modelling Diabetes Anesthesiology Biologicals Endocrinology/Sexual health Lung Diseases Blood disorders