Presentations

Robust fitting of pharmacokinetic models to Phase II/III clinical trial data

Freijer J., Greef I.d., Post T. and Ploeger B., Robust fitting of pharmacokinetic models to Phase II/III clinical trial data. PAGE.(2005). [Link to publication]

Mechanistic Disease Progression Analysis Indicates that Pioglitazone Improves ß-cell Function in Treatment-naïve Type 2 Diabetics

Winter W.d., Jongh J.d., Urquhart R., Moules I., Eckland D. and Danhof M., Mechanistic Disease Progression Analysis Indicates that Pioglitazone Improves ß-cell Function in Treatment-naïve Type 2 Diabetics. ADA.(2005).

Treatment efficacy of Pioglitazone in Combination Therapy

Post T., Winter W.d., Jongh J.d., Urquhart R., Moules I., Eckland D. and Danhof M., Treatment efficacy of Pioglitazone in Combination Therapy on Disease Progression in Type 2 Diabetes Mellitus over a two-year period. ADA.(2005).

Cascading Disease Progression Analysis in Type 2 Diabetes

Winter W.d., Cascading Disease Progression Analysis in Type 2 Diabetes: Integrating multiple biomarkers into single mechanism-based model. PharmSciFair.(2005).

Treatment Efficacy of Combination-Therapy

Post T.M., Winter W.d., Jongh J.d., Moules I., Urquhart R., Eckland D. and Danhof M., Treatment Efficacy of Combination-Therapy based on a Mechanistic Characterisation of Disease Processes in Type 2 Diabetes Mellitus over a two-year period. Figon.(2005).

Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus and Pioglitazone Treatment Effects

Winter W.d., Post T., Jongh J.d., Urquhardt R., Moules I., Eckland D. and Danhof M.A., Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus and Pioglitazone Treatment Effects. PAGE.(2004). [Link to publication]

Reversal of rocuronium-induced neuromuscular block by cyclodextin ORG 25969

Ploeger B., Houwing N., Bom A., Zollinger D. and Danhof M., Reversal of rocuronium-induced neuromuscular block by cyclodextin ORG 25969: model development and validation. PAGE.(2004). [Link to publication]

Development of a mechanism-based PK-PD model of the reversal of rocuronium-induced neuromuscular block by ORG25969

Ruigt G.S., Ploeger B., Danhof M., Bom A., Houwing N. and Iersel M.P.v., Development of a mechanism-based PK-PD model of the reversal of rocuronium-induced neuromuscular block by ORG25969. IARS.(2004). [Link to publication]

Disease Progression Analysis for Type 2 Diabetes Mellitus

Winter W.d., Post T.M., Jongh J.d., Moules I., Urquhart R., Eckland D. and Danhof M., Disease Progression Analysis for Type 2 Diabetes Mellitus: Bridging Therapeutic Intervention and Disease Outcome. Figon.(2004).

Towards a Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus

Winter W.d., Jongh J.d., Eckland D. and Danhof M., Towards a Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus. ASCPT.(2004).