Evaluate the effect of intrinsic and extrinsic factors on regorafenib (REG) exposure

Therapeutic area :

Ploeger B., Cleton A., Keunecke A., Bruix J., Meinhardt G. Population pharmacokinetics (popPK) to evaluate the effect of intrinsic and extrinsic factors on regorafenib (REG) exposure in REG studies including patients with hepatocellular carcinoma (HCC). The American Society of Clinical Oncology – Gastrointestinal Cancers Symposium, 2017.