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Innovative adaptive dose simulations in NONMEM to allow simulation-based model evaluation of titration-based dosing, applied to a population doe-hemoglobin model for daprodustat.

Therapeutic area :

Goulooze S.C., Noort van N., Berg van den P., Yang S., Beerahee M., Mahar K.M., Post T.M. Innovative adaptive dose simulations in NONMEM to allow simulation-based model evaluation of titration-based dosing, applied to a population doe-hemoglobin model for daprodustat. ACoP 2022. Link to publication

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Methods Anti-infectives and immunology General modelling CNS Lung Diseases Oncology Paediatrics Diabetes Gastrointestinal Diseases Biologicals Safety pharmacology Blood disorders Peripheral Nervous System Anesthesiology Pain Cardiovascular Endocrinology/Sexual health