Presentations
Trame M.N., Post T.M. Session 1c: A Perspective on integrating Pharmacometrics and Quantitative Systems Pharmacology characteristics using examples. ACoP9, 2018. [Link to publication]
Post T.M. Application of an iPSP Model with Reduced Mechanistic Detail for a Disease System Analysis applied to Osteoporosis. ACoP9, 2018. [Link to publication]
Fidler M., Wang W., Post T.M., Wilkins J., Schoemaker R., Trame M.N. Tutorial 1: nlmixr: Population Modeling in R. ACoP9, 2018. [Link to publication]
Fidler M, Xiong Y, Schoemaker R, Wilkins J, Trame M.N, Post T.M, Hooijmaijers R, Wang W., Solving sensitivity equations by inductive linearization and its applications in population pharmacokinetic and pharmacodynamic models via FOCEi. ACoP9 2018
Fidler M, Xiong Y, Schoemaker R, Wilkins J, Trame M.N, Post T.M, Hooijmaijers R, Wang W. Exploring inductive linearization in population pharmacokinetic and pharmacodynamic models. ACoP9, 2018.
Ploeger B., Cleton A., Keunecke A., Bruix J., Meinhardt G. Population pharmacokinetics (popPK) to evaluate the effect of intrinsic and extrinsic factors on regorafenib (REG) exposure in REG studies including patients with hepatocellular carcinoma (HCC). The American Society of Clinical Oncology – Gastrointestinal Cancers Symposium, 2017.
Maanen E.M.T.v., Steeg T.J.v., Kalinina J., Michener M.S., Savage M.J., Kennedy M.E., Parker E.M., Danhof M. Systems pharmacology analysis of the Aβ oligomer response following β-secretase inhibition: Evidence for second-order kinetics of Aβ42 oligomerization. AAIC, 2017.
Maanen E.M.T.v., Steeg T.J.v., Kalinina J., Michener M.S., Savage, M.J., Kennedy M.E., Parker E.M., Danhof, M. A systems pharmacology approach unfolds Aβ oligomer modulation and unravels the dynamics of the APP pathway. Page 2017. [Link to publication]
Maanen E.M.T., Steeg, TJ.v., Kalinina J., Stone, J., Michener M.S., Savage M.J., Parker E.M., Danhof, M. Resilience in the Amyloid Precursor Protein ( APP ) pathway revealed by systems pharmacology modeling following β – and γ -secretase inhibition. AAIC, 2017.
Schulthess P., Post T.M., Yates J., Graaf H.J.v.d. Frequency-domain response analysis for quantitative systems pharmacology models. PAGE, 2017. [Link to publication]