Presentations
Maanen E.v., Stone J.A., Steeg T.v., Ahsman M., Savage M.J., Michener M.S. and Kleijn H., A step-wise analysis of multiple biomarkers drives the development of a Semi-Mechanistic Comprehensive Model. Application to modulation of Amyloid-β. PAGE.(2012) [Link to publication]
Maanen E.v., Ackaert O., Snelder N., Bergmann K., Maciag C., Quirk M., Wallsten C. and Ploeger B., Data transformation procedure to improve identifiability of efficacy and potency: Application to continuous elevated plus-maze data in rats., PAGE.(2012) [Link to publication]
Bergmann K., Steeg T.v., Smeets J., Chaudhury C. and Agoram B., Development of a mechanistic based model for neonatal Fc receptor recycling to design human serum albumin mutants with extended half-lives PAGE.(2012) [Link to publication]
Bergmann K., Ackaert O., Maanen E.v., Snelder N., Maciag C., Quirk M., Wallsten C. and Ploeger B., Quantification of Antidepressant and Sedative Effect of Two NMDA Channel Blockers, AZD6765 and Ketamine, in an Animal Model of Depression Using Count Data. PAGE.(2012)
Bergmann K., Ackaert O., Haddish-Berhane N. and Betts A., Comparing a mechanistic with an empirical approach to assess resistance development of antibacterials in vitro., PAGE.(2012) [Link to publication]
Ackaert O., Rijn-Bikker P.v., Snelder N., Hest R.v., Ploeger B., Monfrans G.v., Koopmans R. and Mathot R., Population modeling of blood pressure: assessing clinically important factors for cardiovascular diseases. PAGE.(2011) [Link to publication]
Snelder N., Ploeger B.A., Danhof M., Stanski D.R., Rigel D., Webb R., Feldman D. and Luttringer O., Quantitative understanding of drug effects on the interrelationship between mean arterial blood pressure, cardiac output and total peripheral resistance. PAGE.(2011) [Link to publication]
Maanen E.V., Challenges in Non-Clinical Assessment of Antisense Oligonucleotides: Modelling Perspectives. AAPS (National Biotechnology Conference).(2011)
Diack C., Ackaert O., Ploeger B., Graaf P.v.d., Gurrell R., Ivarsson M. and Fairman D., A true Markov model for sleep disturbance. PAGE.(2010). [Link to publication]
Maanen E. v., Brady K., Steeg T.v. and Graaf P.v.d., A novel integrated RNAi/viral dynamics systems pharmacology model to predict clinical efficacy of viral vector delivery of siRNA for the treatment of HCV. Noordwijkerhout.(2010)