Publications

Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients

Swart E.L., Zuideveld K.P., Jongh J.d., Danhof M., Thijs L.G.  and Strack van Schijndel R.M., Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients, Eur J Clin Pharmacol., 62(3): 185-194., 2006. [Link to publication]

Long-term effects of pioglitazone, metformin and gliclazide

Winter W.d., Jongh J.d, Post T., Ploeger B., Urquhart R., Moules I., Eckland D. and Danhof M., A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus, J Pharmacokinet Pharmacodyn., 33(3): 313-343., 2006. [Link to publication]

Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor

Schaddelee M.P., Collins S.D., Jongh J.d., Boer A.G.d., Ijzerman A.P. and Danhof M., Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain, Eur J Pharmacol, 514(2-3): 131-140, 2005. [Link to publication]

Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients

Swart E.L., Jongh J.d., Zuideveld K.P., Danhof M., Thijs L.G. and Strack van Schijndel R.J., Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltration, Am J Kidney Dis., 45(2): 360-371., 2005. [Link to publication]

Basic disease progression models in degenerative disease

Post T.M., Freijer J.I., Jongh J.d. and Danhof M., Disease system analysis: basic disease progression models in degenerative disease, Pharm Res, 22(7): 1038-1049., 2005. [Link to publication]

Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo

Liefaard L.C., Ploeger B.A., Molthoff C.F., Boellaard R., Lammertsma A.A., Danhof M. and Voskuyl R.A., Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography, Mol Imaging Biol., 7(6): 411-421., 2005. [Link to publication]

Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients

Swart E.L., Zuideveld K.P., Jongh J.d., Danhof M., Thijs L.G. and Strack van Schijndel R.M., Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients, Br J Clin Pharmacol., 57(2): 135-145., 2004. [Link to publication]

Population pharmacokinetic modeling of blood-brain barrier transport of synthetic adenosine A1 receptor agonists

Schaddelee M.P., Groenendaal D., Jongh J.d., Cleypool C.G., AP I.J., Boer A.G. d. and Danhof M., Population pharmacokinetic modeling of blood-brain barrier transport of synthetic adenosine A1 receptor agonists, J Pharmacol Exp Ther, 311(3): 1138-1146, 2004. [Link to publication]

Population pharmacokinetic-pharmacodynamic modelling of the anti-hyperalgesic effect of 5’deoxy-N6-cylopentyladenosine

Schaddelee M.P., Jongh J.d., Collins S.D., Boer A.G.d., Ijzerman A.P. and Danhof M., Population pharmacokinetic-pharmacodynamic modelling of the anti-hyperalgesic effect of 5’deoxy-N6-cylopentyladenosine in the mononeuropathic rat, Eur J Pharmacol, 504(1-2): 7-15, 2004. [Link to publication]

Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients

Knibbe C.A., Zuideveld K.P., Jongh J.d., Kuks P.F., Aarts L.P. and Danhof M. , Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%, Clin Pharmacol Ther. , 72 : 670-84., 2002. [Link to publication]