Publications
Geldof M., Freijer J.I., Beijsterveldt L.v., Langlois X. and Danhof M., Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol., 154(6): 1369-1378. Epub 2008 May 1319., 2008. [Link to publication]
Geldof M., Freijer J.I., Peletier L.A., Beijsterveldt L.v. and Danhof M., Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci., 33(3): 217-229. Epub 2007 Dec 2007., 2008. [Link to publication]
Geldof M., Freijer J., Beijsterveldt L.v. and Danhof M., Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat, Pharm Res., 25(4): 792-804. Epub 2007 Aug 2021., 2008. [Link to publication]
Muller A.E., Jongh J.d., Oostvogel P.M., Voskuyl R.A., Dorr P.J., Danhof M. and Mouton J.W., Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, 198(1): 108 e101-106, 2008. [Link to publication]
Steeg T.J.v., Freijer J., Danhof M. and Lange E. C. d., Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther., 324(3): 1234-1242., 2008. [Link to publication]
Muller A.E., Dorr P.J., Mouton J.W., Jongh J.d., Oostvogel P.M., Steegers E.A., Voskuyl R.A. and Danhof M., The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol., 66(6): 866-874., 2008. [Link to publication]
Post T.M., Freijer J.I., Ploeger B.A. and Danhof M., Extensions to the visual predictive check to facilitate model performance evaluation, J Pharmacokinet Pharmacodyn., 35(2): 185-202. 2008. [Link to publication]
Danhof M., Lange E.C.d, Della Pasqua O.E., Ploeger B.A. and Voskuyl R.A., Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research, Trends Pharmacol Sci., 29(4): 186-191., 2008. [Link to publication]
Groenendaal D., Freijer J., Rosier A., Mik D.d., Nicholls G., Hersey A., Ayrton A.D., Danhof M. and Lange E.C.d., Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci., 34(2-3): 149-163. Epub 2008 Mar 2030., 2008. [Link to publication]
Steeg T.J.v., Freijer J., Danhof M. and Lange E.C.d, Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, 10: 10, 2007. [Link to publication]