Archive for December 2007
Dose Prediction of Tacrolimus in de novo Kidney Transplant Patients with Population Pharmacokinetic Modelling Including Genetic Polymorphisms
Press R.R., Ploeger B.A., Hartigh J.d., Straaten R.J.H.M.v.d., Pelt J.v., Danhof M., Fijter J.W.d. and Guchelaar H.J., Dose Prediction of Tacrolimus in de novo Kidney Transplant Patients with Population Pharmacokinetic Modelling Including Genetic Polymorphisms. PAGE.(2007). [Link to publication]
Read MoreUtility of a mixed effects approach to defining target binding rate constants
Benson N., Snelder N., Ploeger B., Napier C., Sale H. and Graaf P.v.d., Utility of a mixed effects approach to defining target binding rate constants. PAGE.(2007). [Link to publication].
Read MoreDisease system analysis distinguishing disease status from disease process
Jongh J.d., Post T., Freijer J., Winter W.d., Danhof M. and Ploeger B., Disease system analysis distinguishing disease status from disease process. PSWC.(2007).
Read MorePopulation PK/PD analysis of compound X to find appropriate dosage regimen in clinical trial
Funaki T., Post T., Maune H. and Drenth H., Population PK/PD analysis of compound X to find appropriate dosage regimen in clinical trial. PAGE. (2007).
Read MoreMechanism-based model of effect of co-administration of exogenous testosterone and progestogens on the hypogonadalaxis in men
Strougo A., Elassais-Schaap J., Greef R.d. and Drenth H., Mechanism-based model of effect of co-administration of exogenous testosterone and progestogens on the hypogonadalaxis in men. PAGE. (2007). [Link to publication]
Read MoreCircadian rhythm in pharmacodynamics and its influence on the identification of treatment effects
Post T., Funaki T., Maune H. and Drenth H., Circadian rhythm in pharmacodynamics and its influence on the identification of treatment effects. PAGE.(2007). [Link to publication]
Read MorePharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats
Steeg T.J.v., Freijer J., Danhof M. and Lange E.C.d, Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, 10: 10, 2007. [Link to publication]
Read MoreDisease Severity Is a Major Determinant for the Pharmacodynamics of Propofol in Critically Ill Patients
Peeters M.Y., Bras L.J., Jongh J.d., Wesselink R.M., Aarts L.P., Danhof M. and Knibbe C.A., Disease Severity Is a Major Determinant for the Pharmacodynamics of Propofol in Critically Ill Patients, Clin Pharmacol Ther, 8: 8, 2007. [Link to publication]
Read MorePharmacokinetics of penicillin G in infants
Muller A.E., Jongh J.d., Bult Y., Goessens W.H., Mouton J.W., Danhof M. and Anker J.N.v.d., Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, 23: 23, 2007. [Link to publication]
Read MoreApplication of the convection-dispersion equation to modelling oral drug absorption
Freijer J.I., Post T.M., Ploeger B.A., Jongh J.d. and Danhof M., Application of the convection-dispersion equation to modelling oral drug absorption, Bull Math Biol., 69(1): 181-195., 2007. [Link to publication]
Read More