Archive for May 2022
Application of quantitative protein mass spectrometric data in the early predictive analysis of target engagement by monoclonal antibodies.
Muliaditan M, Sepp A. Application of quantitative protein mass spectrometric data in the early predictive analysis of target engagement by monoclonal antibodies. Clin Transl Sci. 2022. [Link to publication]
Read MoreA novel cardiovascular systems model to quantify drugs effects on the inter-relationship between contractility and other hemodynamic variables.
Fu Y., Taghvafard H., Said M.M., Rossman E.I., Collins T.A., Billiald-Desquand S., Leishman D., Graaf van der P.H., Hasselt van C.J.G., Snelder N. A novel cardiovascular systems model to quantify drugs effects on the inter-relationship between contractility and other hemodynamic variables. CPT Pharmacometrics Syst Pharmacol. 2022;00:1–13. [Link to publication].
Read MoreThe Effect of Ibuprofen Exposure and Patient Characteristics on the Closure of the Patent Ductus Arteriosus in Preterm Infants.
Engbers A.G.J., Völler S., Flint R.B., Goulooze S.C., de Klerk J., Krekels E.H.J., van Dijk M., Willemsen S.P., Reiss I.K.M., Knibbe C.A.J., Simons S.H.P. The Effect of Ibuprofen Exposure and Patient Characteristics on the Closure of the Patent Ductus Arteriosus in Preterm Infants. Clin Pharmacol Ther. 2022 [Link to publication]
Read MoreDose-Exposure-Response Analysis of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone on UACR and eGFR: An Analysis from FIDELIO-DKD.
Goulooze S.C., Heerspink H.J.L., van Noort M., Snelder N., Brinker M., Lippert J. Dose-Exposure-Response Analysis of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone on UACR and eGFR: An Analysis from FIDELIO-DKD. T. Clin Pharmacokinet. 2022 [Link to publication].
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