Archive for September 2017
Systems pharmacology analysis of the Aβ oligomer response following β-secretase inhibition
Maanen E.M.T.v., Steeg T.J.v., Kalinina J., Michener M.S., Savage M.J., Kennedy M.E., Parker E.M., Danhof M. Systems pharmacology analysis of the Aβ oligomer response following β-secretase inhibition: Evidence for second-order kinetics of Aβ42 oligomerization. AAIC, 2017.
Read MoreInfluence of Body Composition on Disposition of the Highly Fat Distributed Compound as Analyzed by Physiologically-based Pharmacokinetic (PBPK) Modeling and Simulation
Goto, A., Tagawa, Y., Moriya, Y., Sato, S., Yamamoto, M., Wakabayashi T., Tsukamoto T., Jongh J.d., Steeg T.J.v., Moriwaki T., Asahi, S. Influence of Body Composition on Disposition of the Highly Fat Distributed Compound as Analyzed by Physiologically-based Pharmacokinetic (PBPK) Modeling and Simulation. Biopharmaceutics & Drug Disposition: 543-552, 2017. [Link to publication]
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